全部资讯 > Congratulations to Lei Wang for her papper accepted by Nano Today
Congratulations to Lei Wang for her papper accepted by Nano Today
Electrochemiluminescence (ECL) offers numerous unique advantages for microscopic imaging. However, achieving real-time dynamic observation of biomolecules on cell membranes through ECL imaging remains a challenge. Herein, we present a new ECL nanoemitter for real-time multicolor imaging of biomolecules on cell membranes. The nanoemitter consists of quantum dots (QDs) with surface-immobilized glucose oxidase capable of catalyzing glucose oxidation to produce co-reactant hydrogen peroxide (H2O2). This nanoemitter enables sequential real-time imaging with a relatively high signal-to-noise ratio owing to the continuous availability of co-reactants. Therefore, by using the functionalized multicolor QDs for ECL-based single-particle tracking, the dynamic behaviors of individual biomolecules on cell membranes, including inter-molecular interactions, can be visualized in real time. This new nanoemitter is expected to facilitate investigations of the dynamics of biomolecules on cell membranes.